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Sunday, 20 October 2013

Type 1 diabetes, information of type 1 diabetes

Type 1 diabetes, information of type 1 diabetes

Type 1 diabetes mellitus is characterized by loss of insulin-producing beta cells of the islets of Langerhans in the pancreas, leading to insulin deficiency. This type can be further classified as immune - mediated or idiopathic. Most Type 1 diabetes is immune nature - mediated, in which the loss of beta cells is an autoimmune attack mediated T cell. There is no known preventive measure against type 1 diabetes, which causes approximately 10% of diabetes mellitus cases in North America and Europe. Most affected people are otherwise healthy and of a healthy weight when onset occurs. Type 1 diabetes can affect children or adults but was traditionally termed “juvenile diabetes” because most diabetes cases were in children.

Diabetes "fragile” , also known as unstable diabetes or labile diabetes is a term traditionally used to describe recurrent drastic changes in glucose levels , often occurring for no apparent reason in insulin-dependent diabetes . This term, however, has no biological basis and should not be used. There are many reasons to type 1 diabetes to be accompanied by hyperglycemia irregular and unpredictable , frequently with ketosis , and sometimes serious hypoglycemia , including impairment of counter regulatory response to hypoglycemia , occult infection , gastrointestinal paresis (leading to erratic absorption of carbohydrates from the diet) , and endocrinopathies (eg , Addison's disease ) . These phenomena are thought to occur no more frequently than 1% to 2 % of people with type1 diabetes.

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